Nick Wagoner

49ers defensive lineman Keion White underwent surgery Monday after he was shot in the ankle in San Francisco hours after Super Bowl LX concluded.

Buoyed by a first-half surge in which he outgained the entire Patriots offense, Seahawks running back Kenneth Walker III, a pending unrestricted free agent, earned MVP honors as Seattle ran to a 29...

Cam Newton vs. Peyton Manning was among the notable items from the last time the Bay Area hosted the big game.

Niners GM John Lynch said the team will look into "everything" to find out why injuries continue to pile up year after year, including an investigation into the viral electrical substation conspira...

At Wednesday's end-of-season news conference, 49ers general manager John Lynch confirmed what has been obvious for months: WR Brandon Aiyuk will not return to the only NFL team he has ever known.

Shanahan took a different approach to 2025 -- and it has the 49ers two games away from the Super Bowl.

Kyle Shanahan said Fred Warner will not come off injured reserve this week, ruling him out for Saturday's game in Seattle, but he said he was encouraged that the NFC title game timeline remains in ...

49ers linebacker Fred Warner made it clear Wednesday that he hasn't ruled out returning from a fractured and dislocated right ankle as soon as Saturday night.

George Kittle suffered an injury to his right Achilles in Sunday's wild-card playoff game against the Eagles.

San Francisco will face Philadelphia on Sunday (4:30 p.m. ET) in part because of a strong bond between the duo.

Christian McCaffrey owned a bobbled pass that turned into a game-sealing interception, saying it was a play he had to make. The 49ers were unable to make several key plays in their 13-3 loss to Sea...

George Kittle, who missed the Niners' Sunday night win against the Bears with a sprained left ankle, said he "absolutely" expects to play in Saturday's crucial showdown with the Seahawks.

Niners star Christian McCaffrey missed Tuesday's practice with a stiff back, while left tackle Trent Williams nursed a right hamstring injury ahead of Saturday's showdown with the Seahawks.

For the second week in a row, QB Brock Purdy accounted for five touchdowns as the 49ers outlasted the Bears 42-38 in a wild shootout on Sunday Night Football to set up a Week 18 showdown with the S...

With 44-year-old Colts quarterback Philip Rivers and his comeback occupying most of the headlines entering Monday's game, it was Brock Purdy who stole the show, throwing five touchdown passes in le...

Saleh has the 49ers' defense staying afloat amid injuries and offseason turnover. Could he leave this offseason?

The 49ers placed Brandon Aiyuk on the reserve/left team list on Saturday, likely ending the receiver's tenure in San Francisco.

49ers running back Christian McCaffrey is expected to play vs. the Titans on Sunday, a source said, despite being added to the injury report as questionable.

San Francisco voided the receiver's contract guarantees for next year. What does that mean for this season and beyond?

A resilient 49ers team is welcoming the rest of the upcoming bye week after positioning themselves well for a postseason run with three straight wins.